Team:Hong Kong HKUST/riboregulator
From 2014.igem.org
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<u>CR and TA riboregulator system</u> | <u>CR and TA riboregulator system</u> | ||
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Artificial cis-repressing and trans-activating riboregulator system was introduced to the iGEM community by Isaacs in 2005. | Artificial cis-repressing and trans-activating riboregulator system was introduced to the iGEM community by Isaacs in 2005. |
Revision as of 11:16, 13 October 2014
Riboregulator Project Abstract
Regulatory RNAs are small RNA that regulate biological processes such as transcription or translation. The use of regulatory
RNAs has been a great interest in the field of synthetic biology because it provides an additional level of regulation for
biological circuits and systems. Regulatory RNAs have also been used by many iGEM teams. We have identified 7 teams that have used
cis-repressing (CR) and trans-activating (TA) riboregulator system and more teams that have used riboswitches. For example,
Isaacs 2005, UC Berkeley 2006 and Caltech 2007 contributed many CR and TA devices to the Registry.
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The benefits of this system, as described in Isaacs et al.'s paper, are leakage minimization, fast response time, tunability, independent regulation of multiple genes etc. |