Team:Hong Kong HKUST/pneumosensor

From 2014.igem.org

(Difference between revisions)
Line 108: Line 108:
<div class= "content_area_two_row">
<div class= "content_area_two_row">
-
<div class="content_image">
+
<div class="content_image" align="center">
-
<img align="center" style="width:85%;height:85%"src= "https://static.igem.org/mediawiki/2014/b/b6/HKUST_iGEM_2014_M1abstractv2.png"/>
+
<img style="width:85%;height:85%"src= "https://static.igem.org/mediawiki/2014/b/b6/HKUST_iGEM_2014_M1abstractv2.png"/>
<div><h5>Fig 1 . Here is the potato.</h5>
<div><h5>Fig 1 . Here is the potato.</h5>
<h6> Here is the description of the potato: it is a potato!</h6></div>
<h6> Here is the description of the potato: it is a potato!</h6></div>

Revision as of 16:08, 3 October 2014


Pneumosensor Project Abstract

Fig 1 . Here is the potato.
Here is the description of the potato: it is a potato!

Streptococcus pneumoniae is responsible for approximately 1.6 million deaths every year mostly in developing countries where vaccination is unaffordable. To provide an affordable solution to combat pneumococcal diseases, we are engineering an E. coli "Pneumosensor", that will work inside an in vitro diagnostic device. Through this cheaper and easier diagnosis method, people can prepare themselves better against the transmission and adversity of S. Pneumoniae.

Pneumosensor has a rewired comCDE signal transduction pathway native to S. pneumoniae that detects autoinducer molecules released specifically by S. pneumoniae. It is also equipped with a new promoter for the specific and tight regulation of target gene expression in E. coli. In addition, the team is documenting and characterizing existing CR-TA riboregulators for post-transcriptional regulation of gene expression. Our work will help other iGEM teams more effectively incorporate this tuning tool into their project design.


Home

Pneumosensor

Riboregulator

Human Practice

Team

WetLab

Achievement