Team:Groningen/Template/MODULE/project/bandage/materials

From 2014.igem.org

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* 20% PolyAcrylamide 1% crosslinked
* 20% PolyAcrylamide 1% crosslinked
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*0.2 micrometers bottom membrane, Cellulose nitrate - Ultipore Nylon
*0.2 micrometers bottom membrane, Cellulose nitrate - Ultipore Nylon
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*TPX top membrane (from the iGEM Groningen 2012 team)
*TPX top membrane (from the iGEM Groningen 2012 team)
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*Small pore size (0.2 micron)
*Small pore size (0.2 micron)
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* Permeable to proteins
* Permeable to proteins
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*Hydrophilic
*Hydrophilic
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*Flexible
*Flexible
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*Shouldn't stick to a wound
*Shouldn't stick to a wound
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Revision as of 22:48, 17 October 2014

Materials
 

  • 20% PolyAcrylamide 1% crosslinked
  • 0.2 micrometers bottom membrane, Cellulose nitrate - Ultipore Nylon
  • TPX top membrane (from the iGEM Groningen 2012 team)

We've been through a long track before we were able to choose our final materials. We started by thinking of the molecules that should be able to stay inside the bandage and also those that should diffuse outside of it. Taken in account that we have 3 molecules that need to diffuse outside of our bandage and also several ones that need to go inside. With this in our mind we knew we needed a bottom layer that is able of keeping the bacteria inside while diffusing the molecules. So our demands for the bottom layer are:
 

  • Small pore size (0.2 micron)
  • Permeable to proteins
  • Hydrophilic
  • Flexible
  • Shouldn't stick to a wound

We at first thought of using Polysulfone, polyamide 66 or an acrylate copolymer. After consulting with several company's they came up with several idea's which are: Ultipore Nylon and EKV/PES (Pall) and a Cellulose Nitrate membrane (Sartorius) All of these could work fine although we'd prefer working with a transparent membrane. After all our research we couldn't find a membrane which was transparent.