Team:ETH Zurich/modeling/xor

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== Model ==
== Model ==
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Each fragment that can be flipped by integrases is surrounded by two DNA-binding sites. Those sites correspond to the binding sites of a particular integrase. In our model, the flipping fragment is made of a terminator. Therefore, this fragment is modeled via two states:
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After [https://2014.igem.org/Team:ETH_Zurich/modeling/int binding to DNA], integrases can flip the fragment and thus compute the output of the XOR logic gate.  
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=== Principle ===
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* T<sub>on</sub>: terminator is on, transcription is blocked. It corresponds to our initial state.
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The fragment integrases can be flip is a terminator. Thus, the terminator can either be on or off.
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* T<sub>on</sub>: terminator is on, transcription is blocked.  
* T<sub>off</sub>: terminator is off, transcription is active. It corresponds to one flipping of the terminator.
* T<sub>off</sub>: terminator is off, transcription is active. It corresponds to one flipping of the terminator.
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In our design, we are interested in a double flipping.
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In our design, we are interested in a double flipping. That is to say that two pairs of binding sites surrounds the fragment to be flipped. One pair of binding sites can be bound by DBxb1 and the other one by ΦC31.
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Revision as of 11:23, 13 October 2014

iGEM ETH Zurich 2014