# Team:ETH Zurich/modeling/whole

(Difference between revisions)
 Revision as of 23:35, 17 October 2014 (view source)Lnadine (Talk | contribs) (→With Leakiness)← Older edit Revision as of 23:36, 17 October 2014 (view source)Lnadine (Talk | contribs) (→With Leakiness)Newer edit → Line 261: Line 261: - [[File:ETHZ_Leakiness.png|center|800px|thumb|The four cases for the whole cell with basal leakiness]] + [[File:ETHZ_Leakiness.png|center|800px|thumb|'''Figure 6''' The four cases for the whole cell with basal leakiness]] From our experimental data, we observed some basal leakiness for PLux and PLas even after using riboregulators. From the model we see that, this small basal leakiness is amplified downstream. The basal leakiness results in production of integrases which further act on the XOR module and cause the switching of the terminator. Thus, there is GFP and LasI produced, and the LasI produced further catalyses the production of more LasAHL. Thus, we observe some GFP even without inputs. From our experimental data, we observed some basal leakiness for PLux and PLas even after using riboregulators. From the model we see that, this small basal leakiness is amplified downstream. The basal leakiness results in production of integrases which further act on the XOR module and cause the switching of the terminator. Thus, there is GFP and LasI produced, and the LasI produced further catalyses the production of more LasAHL. Thus, we observe some GFP even without inputs. - + Line 280: Line 280: - [[File:ETHZ_XORWholeCellwithLeakiness.png|center|800px|thumb|Predicted XOR behaviour for the whole cell model with leakiness]] + [[File:ETHZ_XORWholeCellwithLeakiness.png|center|800px|thumb|'''Figure 8''' Predicted XOR behaviour for the whole cell model with leakiness]] === With Leakiness and Crosstalk === === With Leakiness and Crosstalk ===

## Revision as of 23:36, 17 October 2014

iGEM ETH Zurich 2014