# Team:ETH Zurich/modeling/qs

(Difference between revisions)
 Revision as of 07:58, 17 October 2014 (view source)Eledieu (Talk | contribs)m (→Cross-talk)← Older edit Revision as of 07:59, 17 October 2014 (view source)Eledieu (Talk | contribs) m (→Leakiness)Newer edit → Line 229: Line 229: The leakiness of promoters is a major issue in our system. As the signal propagates row-wise, error diffusion could lead to a totally different pattern. The goal is then to control the leakiness. This issue was particularly observed and adressed in the case of the Lux promoter during our [http://2014.igem.org/Team:ETH_Zurich/expresults experiments set]. This leakiness is dependent on LuxR concentration in the cell(see our biobrick characterization in the [http://parts.igem.org/Part:BBa_R0062:Experience Registry] for more information). The leakiness of promoters is a major issue in our system. As the signal propagates row-wise, error diffusion could lead to a totally different pattern. The goal is then to control the leakiness. This issue was particularly observed and adressed in the case of the Lux promoter during our [http://2014.igem.org/Team:ETH_Zurich/expresults experiments set]. This leakiness is dependent on LuxR concentration in the cell(see our biobrick characterization in the [http://parts.igem.org/Part:BBa_R0062:Experience Registry] for more information). - +
Leakiness was modeled as an offset in the classical Hill function. Leakiness was modeled as an offset in the classical Hill function.

## Revision as of 07:59, 17 October 2014

iGEM ETH Zurich 2014