Team:ETH Zurich/modeling/qs

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The leakiness of promoters is a major issue in our system. As the signal propagates row-wise, error diffusion could lead to a totally different pattern. The goal is then to control the leakiness. This issue was particularly observed and adressed in the case of the Lux promoter during our [http://2014.igem.org/Team:ETH_Zurich/expresults experiments set]. This leakiness is dependent on LuxR concentration in the cell(see our biobrick characterization in the [http://parts.igem.org/Part:BBa_R0062:Experience Registry] for more information).
The leakiness of promoters is a major issue in our system. As the signal propagates row-wise, error diffusion could lead to a totally different pattern. The goal is then to control the leakiness. This issue was particularly observed and adressed in the case of the Lux promoter during our [http://2014.igem.org/Team:ETH_Zurich/expresults experiments set]. This leakiness is dependent on LuxR concentration in the cell(see our biobrick characterization in the [http://parts.igem.org/Part:BBa_R0062:Experience Registry] for more information).
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Leakiness was modeled as an offset in the classical Hill function.  
Leakiness was modeled as an offset in the classical Hill function.  

Revision as of 07:59, 17 October 2014

iGEM ETH Zurich 2014