# Team:ETH Zurich/modeling/int

(Difference between revisions)
 Revision as of 00:56, 18 October 2014 (view source)Luwidmer (Talk | contribs) (→Data)← Older edit Revision as of 01:00, 18 October 2014 (view source)Eledieu (Talk | contribs) mNewer edit → Line 12: Line 12: == Model == == Model == - In our design, integrases compute the output of the logic gates. Integrases allow to flip one fragment of DNA. The model we developed is described here. + In our design, integrases compute the output of the logic gates. Integrases allow flipping one fragment of DNA. Therefore, they are of central importance to our design. However, their characterization in literature[[Team:ETH_Zurich/project/references|[9]]] is incomplete. In particular, quantitative insight into dimerization rates and DNA-binding rates is lacking. Such data is however necessary in order to be able to set up a mathematical model to describe the overall Mosai''coli'' process. Thus, we decided to estimate the missing parameters from published from published experiments based on a model that we developed ourselves.

## Revision as of 01:00, 18 October 2014

iGEM ETH Zurich 2014