Team:ETH Zurich/modeling/int

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(Difference between revisions)
(Assumptions)
(Assumptions)
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* The degradation rate of Bxb1, d<sub>Bxb1</sub>, is related to the degradation rate of DBxb1, d<sub>DBxb1</sub>, by a factor 2. d<sub>Bxb1</sub> = 2 * d<sub>DBxb1</sub>
* The degradation rate of Bxb1, d<sub>Bxb1</sub>, is related to the degradation rate of DBxb1, d<sub>DBxb1</sub>, by a factor 2. d<sub>Bxb1</sub> = 2 * d<sub>DBxb1</sub>
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* The activation by aTc is assumed to be dominant over degradation of Bxb1 and dimerization of Bxb1.
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* The activation by aTc is assumed to be dominant over degradation of Bxb1 and dimerization of Bxb1. It is supposed to be valid on the range of aTc concentration considered.
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$$\frac{k_{mRNA_{Bxb1}}*(A_L + B_L * \frac{[aTc]^n}{[aTc]^n+K_L^n})}{d_{Bxb1}K_{DBxb1}} >> 1$$
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with $$K_{DBxb1} = \frac{k_{-DBxb1} + d_{DBxb1}}{k_{DBxb1}$$
=== Parameter fitting ===
=== Parameter fitting ===

Revision as of 11:21, 12 October 2014

iGEM ETH Zurich 2014