Team:ETH Zurich/modeling/diffmodel

From 2014.igem.org

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The main experiment for investigating diffusion is a propagation of the whole pattern through the chip via the quorum sensing module only. We have used beads containing cells which are able to sense luxAHL, produce GFP when they sense it, and amplify the signal for the next row. The combination of the quorum sensing module with diffusion enables to check that cells will amplify the signal enough from one row to the next one, and to check what would be the time scale of the pattern formation. We used a reaction-diffusion model to combine quorum sensing reactions and diffusion.  
The main experiment for investigating diffusion is a propagation of the whole pattern through the chip via the quorum sensing module only. We have used beads containing cells which are able to sense luxAHL, produce GFP when they sense it, and amplify the signal for the next row. The combination of the quorum sensing module with diffusion enables to check that cells will amplify the signal enough from one row to the next one, and to check what would be the time scale of the pattern formation. We used a reaction-diffusion model to combine quorum sensing reactions and diffusion.  
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=== '''Geometry and boundary conditions''' ===
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=== Geometry and boundary conditions ===
[[File:ETH Zurich Compartments Diffusion.png|float|500px|thumb|Millifluidic compartments used for the diffusion model]]
[[File:ETH Zurich Compartments Diffusion.png|float|500px|thumb|Millifluidic compartments used for the diffusion model]]
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$$\text{for every vector n normal to the surface of a bead}$$
$$\text{for every vector n normal to the surface of a bead}$$
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=== '''Species and reactions'''===
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=== Species and reactions ===
{| class="wikitable"
{| class="wikitable"

Revision as of 08:24, 16 October 2014

iGEM ETH Zurich 2014