Team:ETH Zurich/lab/chip

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Our project aims for the biological implementation of [https://2014.igem.org/Team:ETH_Zurich/project/background/modeling#Cellular_Automata cellular automata], so we had to find a way to create a regular grid of cells with a defined neighborhood as shown in the figures below. On the left side a classical cellular automata is depicted (see figure 1), on the right side an outline of [https://2014.igem.org/Team:ETH_Zurich/project/overview#Implementation_in_E._coli our biological version] consisting of a grid-like polydimethylsiloxane (PDMS) chip filled with [https://2014.igem.org/Team:ETH_Zurich/lab/bead cell colonies encapsulated in alginate beads] (see figure 2).
Our project aims for the biological implementation of [https://2014.igem.org/Team:ETH_Zurich/project/background/modeling#Cellular_Automata cellular automata], so we had to find a way to create a regular grid of cells with a defined neighborhood as shown in the figures below. On the left side a classical cellular automata is depicted (see figure 1), on the right side an outline of [https://2014.igem.org/Team:ETH_Zurich/project/overview#Implementation_in_E._coli our biological version] consisting of a grid-like polydimethylsiloxane (PDMS) chip filled with [https://2014.igem.org/Team:ETH_Zurich/lab/bead cell colonies encapsulated in alginate beads] (see figure 2).
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[[File:ETH Zurich Rule 6.PNG|300px|thumb|left|'''Figure 1''' Classical grid from cellular automata theory (ON state=back, OFF state=white).]]
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[[File:ETH Zurich Rule 6.PNG|300px|thumb|left|'''Figure 1''' C'''lassical grid from cellular automata theory''' (ON state=back, OFF state=white).]]
[[File:ETH_Zurich_2014_theoretical_grid.png|300px|thumb|right|'''Figure 2''' Outline of a PDMS-made grid loaded with cells confined in alginate beads for the biological implementation of cellular automata (ON state=sfGFP/green, OFF state=white).]]
[[File:ETH_Zurich_2014_theoretical_grid.png|300px|thumb|right|'''Figure 2''' Outline of a PDMS-made grid loaded with cells confined in alginate beads for the biological implementation of cellular automata (ON state=sfGFP/green, OFF state=white).]]

Revision as of 23:32, 17 October 2014

iGEM ETH Zurich 2014