Team:CityU HK/HumanPractice/Presentation


Revision as of 01:30, 28 August 2014 by Marialilokyee (Talk | contribs)

{{Template:Team:CityU_HK/CSS}} .btn-custom { padding: 8px 30px 8px 30px; background: none; -moz-box-shadow: 3px 3px 5px 6px #000; -webkit-box-shadow: 3px 3px 5px 6px #000; box-shadow: 3px 3px 5px 6px #000; border: solid 2.5px #fff; font-family: 'Oswald', sans-serif; font-size: 20px; } .btn-custom:link { /*overwrite igem default style*/ color: #fff; } .btn-custom:hover { color: #3CC; border: solid 2.5px #3cc; background-color: rgba(255,255,255,0.2); } body { margin: 0; } .carousel-inner { -webkit-box-shadow: 0 8px 6px -6px black; -moz-box-shadow: 0 8px 6px -6px black; box-shadow: 0 8px 6px -6px black; } .carousel-inner .carousel-caption { padding-top: 100px; padding-bottom: 100px; } .carousel-inner .carousel-caption h1 { font-family: 'Pacifico', cursive; font-size: 80px; padding-bottom:15px; } .carousel-inner .carousel-caption h3 { font-size: 60px; font-family: 'Oswald', sans-serif; padding-bottom: 10px; } #abstract { background: #CBEBE3; } #abstract h2{ text-align: center; color: #069; font-family: 'Lobster', cursive; text-shadow:0 0 1px rgba(0,0,0,.2), 0 1px 2px rgba(0,0,0,.3); padding-top: 50px; border-bottom: solid 1px #a9b2bb; margin-left:300px; margin-right:300px; } #abstract p { font-family: 'Dosis', sans-serif; color: #666; line-height: 2em; text-align: justify; padding-left: 200px; padding-right:200px; padding-top: 30px; padding-bottom: 100px; font-size: 14px; } @media screen and (max-width: 480px) { .navbar-default { height: auto;} .navbar-brand { padding-top:10px; font-size: 25px;} .carousel-inner { height:auto;} #abstract h2 { margin-left: 30px; margin-right: 30px;} #abstract p { padding-left: 10px; padding-right: 10px;} #footer img { width: 30px; height: 30px;} }


Obesity has now reached epidemic proportions worldwide, which has serious consequences because obesity is associated with various chronic human diseases such as diabetes, hypertension and cardiovascular diseases. With the aim to protect oneself against obesity and debilitating diseases caused by a high-fat diet, we are using a synthetic biology approach to design an Escherichia coli strain (called Fit Coli) that has an enhanced ability to uptake and convert excess fatty acids from fatty foods into a-linolenic acid (ALA). The strategy is to engineer the fadL and fadD genes along with three desaturase genes to facilitate the uptake of long-chain fatty acids and their biotransformation to ALA by the “Fit Coli” strain. It is predicted that the ALA converted from excess fatty acids by Fit Coli is converted to docosahexaenoic acid (DHA), an omega-3-fatty acid, in the human gut, which is well known to have many positive health benefits.