Team:Aberdeen Scotland/Modeling/Assay

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<p>Hi, there. We are a team of Aberdeen Uni undergrads trying to do our part in the fight against Sleeping Sickness. There's six of us - 5 biologists and 1 physicist.
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<p>A crucial part of the assay is the antibody-to-antigen binding. In this section we try to analyse its behaviour and try to determine if the system is going to have the appropriate amount of sensitivity.</p>
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We are very excited to be able to take part in iGEM and we would like to take you on a tour around our project.</p>
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<p>We have worked all summer towards what we hope would turn out to be some peace of mind for a lot of people. The goal is to develop a novel method for diagnosing
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<p>We have looked at a simple model, which can be illustrated by the following equations:</p>
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Trypanosomiasis. A simpler, cheaper alternative to current methods that would be more versatile in developing countries and their remote regions. We wish to create a
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$$\frac{d[A-a]}{dt}=k_a[A][a]
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test that would be portable, endure harsh environmental conditions and most importantly be sensitive to the early stages of the disease.</p>
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  \frac{d[A]}{dt}=-k_a[A][a]
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<p>This would give a lot of unsuspecting sufferers the chance to get diagnosed early. This way they can get cured quickly, before the disease reaches its later
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  \frac{d[a]}{dt}=-k_a[A][a]$$
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stages, when it is virtually incurable.</p>
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<h3>References</h3>
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<p>[1] </p>
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Revision as of 20:48, 17 October 2014

Team:Aberdeen Scotland/Modelling - 2014.ogem.org



Assay Model


A crucial part of the assay is the antibody-to-antigen binding. In this section we try to analyse its behaviour and try to determine if the system is going to have the appropriate amount of sensitivity.

We have looked at a simple model, which can be illustrated by the following equations:

$$\frac{d[A-a]}{dt}=k_a[A][a] \frac{d[A]}{dt}=-k_a[A][a] \frac{d[a]}{dt}=-k_a[A][a]$$

References

[1]



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