Team:UGA-Georgia/Modeling

Our Model

Idea:

To increase geraniol yield by mapping the entire lipid biosynthesis pathway in M. maripaludis, performing a genome-scale flux balance analysis and developing strategies for the over production of isoprenoid compounds.

Results:

We designed a metabolic model for isoprenoid biosynthesis based upon the complete pathway, including stoichiometric values of acetyl-CoA, ATP, and other compounds required for cell growth. The Biocyc, KEGG, IMG, and SEED databases were used to identify candidate genes/enzymesresponsible for each reaction.