Team:Harvard BioDesign/Project

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HARVARD iGEM 2014!

PROJECT


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Project Description

Content

For the 2014 iGEM competition, the Harvard team aims to adapt E. coli biofilms into an information encoding and storage system. E. coli cells naturally secrete a protein called curli into their extracellular matrix that self-assembles into ordered, linear, amyloid fibers important for the structural integrity of the biofilm. In our system, bacteria will be engineered to produce a variety of curli subunits in response to environmental inputs.

For the 2014 iGEM competition, the Harvard team aims to adapt E. coli biofilms into an information encoding and storage system. E. coli cells naturally secrete a protein called curli into their extracellular matrix that self-assembles into ordered, linear, amyloid fibers important for the structural integrity of the biofilm. In our system, bacteria will be engineered to produce a variety of curli subunits in response to environmental inputs.


References

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  1. Overall project summary
  2. Project Details
  3. Materials and Methods
  4. The Experiments
  5. Results
  6. Data analysis
  7. Conclusions

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